IUBMB Enzyme Nomenclature


Accepted name: CTP-dependent riboflavin kinase

Reaction: CTP + riboflavin = CDP + FMN

Other name(s): Methanocaldococcus jannaschii Mj0056; Mj0056

Systematic name: CTP:riboflavin 5'-phosphotransferase

Comments: This archaeal enzyme differs from EC, riboflavin kinase, in using CTP as the donor nucleotide. UTP, but not ATP or GTP, can also act as a phosphate donor but it is at least an order of magnitude less efficient than CTP.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number:


1. Ammelburg, M., Hartmann, M.D., Djuranovic, S., Alva, V., Koretke, K.K., Martin, J., Sauer, G., Truffault, V., Zeth, K., Lupas, A.N. and Coles, M. A CTP-dependent archaeal riboflavin kinase forms a bridge in the evolution of cradle-loop barrels. Structure 15 (2007) 1577-1590. [PMID: 18073108]

[EC created 2008]

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