IUBMB Enzyme Nomenclature

EC 2.7.1.48

Accepted name: uridine kinase

Reaction: ATP + uridine = ADP + UMP

Other name(s): pyrimidine ribonucleoside kinase; uridine-cytidine kinase; uridine kinase (phosphorylating); uridine phosphokinase

Systematic name: ATP:uridine 5'-phosphotransferase

Comments: Cytidine can act as acceptor; GTP and ITP can act as donors.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9026-39-5

References:

1. Orengo, A. Regulation of enzymic activity by metabolites. I. Uridine-cytidine kinase of Novikoff ascites rat tumor. J. Biol. Chem. 244 (1969) 2204-2209. [PMID: 5782006]

2. Sköld, O. Uridine kinase from Erlich ascites tumor: purification and properties. J. Biol. Chem. 235 (1960) 3273-3279.

[EC 2.7.1.48 created 1965]


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