IUBMB Enzyme Nomenclature

EC 2.7.1.91

Accepted name: sphinganine kinase

Reaction: ATP + sphinganine = ADP + sphinganine 1-phosphate

Other name(s): dihydrosphingosine kinase; dihydrosphingosine kinase (phosphorylating); sphingosine kinase (phosphorylating)

Systematic name: ATP:sphinganine 1-phosphotransferase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 50864-48-7

References:

1. Stoffel, W., Bauer, E. and Stahl, J. The metabolism of sphingosine bases in Tetrahymena pyriformis. Sphingosine kinase and sphingosine-1-phosphate lyase. Hoppe-Seyler's Z. Physiol. Chem. 355 (1974) 61-74. [PMID: 4373374]

2. Stoffel, W., Heimann, G. and Hellenbroich, B. Sphingosine kinase in blood platelets. Hoppe-Seyler's Z. Physiol. Chem. 354 (1973) 562-566. [PMID: 4372149]

[EC 2.7.1.91 created 1976, modified 1980]


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