IUBMB Enzyme Nomenclature

EC 2.7.4.4

Accepted name: nucleoside-phosphate kinase

Reaction: ATP + nucleoside phosphate = ADP + nucleoside diphosphate

For diagram of reaction click here.

Other names: NMP-kinase

Systematic name: ATP:nucleoside-phosphate phosphotransferase

Comments: Many nucleotides can act as acceptors; other nucleoside triphosphates can act instead of ATP.

Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, CAS registry number: 9026-50-0

References:

1. Gibson, D.M., Ayengar, P. and Sanadi, D.R. Transphosphorylations between nucleoside phosphates. Biochim. Biophys. Acta 21 (1956) 86-91.

2. Heppel, L.A., Strominger, J.L. and Maxwell, E.S. Nucleoside monophosphate kinases. II. Transphosphorylation between adenosine monophosphate and nucleotide triphosphate. Biochim. Biophys. Acta 32 (1959) 422-430.

3.Lieberman, I., Kornberg, A. and Simms, E.S. Enzymatic synthesis of nucleotide diphosphates and triphosphates. J. Biol. Chem. 215 (1955) 429-440.

4. Noda, L. Nucleoside triphosphate-nucleoside monophosphokinases, in Boyer, P.D., Lardy, H. and Myrbäck, K. (Eds.), The Enzymes, 2nd edn., vol. 6, Academic Press, New York, 1962, pp.139-149.

[EC 2.7.4.4 created 1961]


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