IUBMB Enzyme Nomenclature

EC 2.7.4.7

Accepted name: phosphomethylpyrimidine kinase

Reaction: ATP + (4-amino-2-methylpyrimidin-5-yl)methyl phosphate = ADP + (4-amino-2-methylpyrimidin-5-yl)methyl diphosphate

For diagram of reaction click here.

Other names: hydroxymethylpyrimidine phosphokinase; ATP:4-amino-2-methyl-5-phosphomethylpyrimidine phosphotransferase

Systematic name: ATP:(4-amino-2-methylpyrimidin-5-yl)methyl-phosphate phosphotransferase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 37278-18-5

References:

1. Lewin, L.M. and Brown, G.M. The biosynthesis of thiamine. III. Mechanism of enzymatic formation of the pyrophosphate ester of 2-methyl-4-amino-5-hydroxymethylpyrimidine. J. Biol. Chem. 236 (1961) 2768-2771.

[EC 2.7.4.7 created 1965]


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