Reaction: ATP + (4-amino-2-methylpyrimidin-5-yl)methyl phosphate = ADP + (4-amino-2-methylpyrimidin-5-yl)methyl diphosphate
For diagram of reaction click here.
Other names: hydroxymethylpyrimidine phosphokinase; ATP:4-amino-2-methyl-5-phosphomethylpyrimidine phosphotransferase
Systematic name: ATP:(4-amino-2-methylpyrimidin-5-yl)methyl-phosphate phosphotransferase
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 37278-18-5
1. Lewin, L.M. and Brown, G.M. The biosynthesis of thiamine. III. Mechanism of enzymatic formation of the pyrophosphate ester of 2-methyl-4-amino-5-hydroxymethylpyrimidine. J. Biol. Chem. 236 (1961) 2768-2771.