IUBMB Enzyme Nomenclature


Accepted name: GTP diphosphokinase

Reaction: ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate

Other name(s): stringent factor; guanosine 3',5'-polyphosphate synthase; GTP pyrophosphokinase; ATP-GTP 3'-diphosphotransferase; guanosine 5',3'-polyphosphate synthetase; (p)ppGpp synthetase I; (p)ppGpp synthetase II; guanosine pentaphosphate synthetase; GPSI; GPSII

Systematic name: ATP:GTP 3'-diphosphotransferase

Comments: GDP can also act as acceptor.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 63690-89-1


1. Fehr, S. and Richter, D. Stringent response of Bacillus stearothermophilus: evidence for the existence of two distinct guanosine 3',5'-polyphosphate synthetases. J. Bacteriol. 145 (1981) 68-73. [PMID: 6161916]

2. Sy, J. and Akers, H. Purification and properties of guanosine 5',3'-polyphosphate synthetase from Bacillus brevis. Biochemistry 15 (1976) 4399-4403. [PMID: 184817]

[EC created 1981]

Return to EC 2.7.6 home page
Return to EC 2.7 home page
Return to EC 2 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page