IUBMB Enzyme Nomenclature

EC 2.7.7.13

Accepted name: mannose-1-phosphate guanylyltransferase

Reaction: GTP + α-D-mannose 1-phosphate = diphosphate + GDP-mannose

For diagram click here.

Other name(s): GTP—mannose-1-phosphate guanylyltransferase; PIM-GMP (phosphomannose isomerase-guanosine 5'-diphospho-D-mannose pyrophosphorylase); GDP-mannose pyrophosphorylase; guanosine 5'-diphospho-D-mannose pyrophosphorylase; guanosine diphosphomannose pyrophosphorylase; guanosine triphosphate-mannose 1-phosphate guanylyltransferase; mannose 1-phosphate guanylyltransferase (guanosine triphosphate)

Systematic name: GTP:α-D-mannose-1-phosphate guanylyltransferase

Comments: The bacterial enzyme can also use ITP and dGTP as donors.

Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, CAS registry number: 37278-24-3

References:

1. Munch-Peterson, A. Enzymatic synthesis and phosphorolysis of guanosine diphosphate mannose. Arch. Biochem. Biophys. 55 (1955) 592-593.

2. Preiss, J. and Wood, E. Sugar nucleotide reactions in Arthrobacter. I. Guanosinediphosphate mannose pyrophosphorylase: purification and properties. J. Biol. Chem. 239 (1964) 3119-3126.

[EC 2.7.7.13 created 1961, modified 1976]


Return to EC 2.7.7 home page
Return to EC 2.7 home page
Return to EC 2 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page