IUBMB Enzyme Nomenclature


Accepted name: choline-phosphate cytidylyltransferase

Reaction: CTP + phosphocholine = diphosphate + CDP-choline

Other name(s): phosphorylcholine transferase; CDP-choline pyrophosphorylase; CDP-choline synthetase; choline phosphate cytidylyltransferase; CTP-phosphocholine cytidylyltransferase; CTP:phosphorylcholine cytidylyltransferase; cytidine diphosphocholine pyrophosphorylase; phosphocholine cytidylyltransferase; phosphorylcholine cytidylyltransferase; phosphorylcholine:CTP cytidylyltransferase; CTP:choline-phosphate cytidylyltransferase

Systematic name: CTP:phosphocholine cytidylyltransferase

Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, PDB, CAS registry number: 9026-34-0


1. Borkenhagen, L.F. and Kennedy, E.P. The enzymatic synthesis of cytidine diphosphate choline. J. Biol. Chem. 227 (1957) 951-962.

2. Kennedy, E.P. and Weiss, S.B. The function of cytidine coenzymes in the biosynthesis of phospholipides. J. Biol. Chem. 222 (1956) 193-214.

3. Williams-Ashman, H.G. and Banks, J. Participation of cytidine coenzymes in the metabolism of choline by seminal vesicles. J. Biol. Chem. 223 (1956) 509-521.

[EC created 1961]

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