IUBMB Enzyme Nomenclature


Accepted name: glucose-1-phosphate thymidylyltransferase

Reaction: dTTP + α-D-glucose 1-phosphate = diphosphate + dTDP-α-D-glucose

For diagram click here.

Other names: glucose 1-phosphate thymidylyltransferase; dTDP-glucose synthase; dTDP-glucose pyrophosphorylase; thymidine diphosphoglucose pyrophosphorylase; thymidine diphosphate glucose pyrophosphorylase; TDP-glucose pyrophosphorylase

Systematic name: dTTP:α-D-glucose-1-phosphate thymidylyltransferase

Comments: Involved in the biosynthesis of L-rhamnose in bacteria.

Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, PDB, CAS registry number: 9026-03-3


1. Kornfeld, S. and Glaser, L. The enzymic synthesis of thymidine-linked sugars. I. Thymidine diphosphate glucose. J. Biol. Chem. 236 (1961) 1791-1794.

2. Pazur, J.H. and Shuey, E.W. The enzymatic synthesis of thymidine diphosphate glucose and its conversion to thymidine diphosphate rhamnose. J. Biol. Chem. 236 (1961) 1780-1785.

[EC created 1965]

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