Reaction: dTTP + α-D-glucose 1-phosphate = diphosphate + dTDP-α-D-glucose
For diagram click here.
Other names: glucose 1-phosphate thymidylyltransferase; dTDP-glucose synthase; dTDP-glucose pyrophosphorylase; thymidine diphosphoglucose pyrophosphorylase; thymidine diphosphate glucose pyrophosphorylase; TDP-glucose pyrophosphorylase
Systematic name: dTTP:α-D-glucose-1-phosphate thymidylyltransferase
Comments: Involved in the biosynthesis of L-rhamnose in bacteria.
Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, PDB, CAS registry number: 9026-03-3
1. Kornfeld, S. and Glaser, L. The enzymic synthesis of thymidine-linked sugars. I. Thymidine diphosphate glucose. J. Biol. Chem. 236 (1961) 1791-1794.
2. Pazur, J.H. and Shuey, E.W. The enzymatic synthesis of thymidine diphosphate glucose and its conversion to thymidine diphosphate rhamnose. J. Biol. Chem. 236 (1961) 1780-1785.