IUBMB Enzyme Nomenclature


Accepted name: N-acylneuraminate cytidylyltransferase

Reaction: CTP + N-acylneuraminate = diphosphate + CMP-N-acylneuraminate

For diagram of reaction click here.

Other name(s): CMP-sialate pyrophosphorylase; CMP-sialate synthase; cytidine 5'-monophosphosialic acid synthetase; CMP-Neu5Ac synthetase; CMP-NeuAc synthetase; acylneuraminate cytidyltransferase; CMP-N-acetylneuraminate synthetase; CMP-N-acetylneuraminate synthase; CMP-N-acetylneuraminic acid synthase; CMP-NANA synthetase; CMP-sialate synthetase; CMP-sialic synthetase; cytidine 5'-monophospho-N-acetylneuraminic acid synthetase; cytidine 5-monophosphate N-acetylneuraminic acid synthetase; cytidine monophosphosialic acid synthetase; cytidine monophosphoacetylneuraminic synthetase; cytidine monophosphosialate pyrophosphorylase; cytidine monophosphosialate synthetase; acetylneuraminate cytidylyltransferase

Systematic name: CTP:N-acylneuraminate cytidylyltransferase

Comments: Acts on N-acetyl- and N-glycolyl- derivatives.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9067-82-7


1. Kean, E.L. and Roseman, S. The sialic acids. X. Purification and properties of cytidine 5'-monophosphosialic acid synthetase. J. Biol. Chem. 241 (1966) 5643-5650. [PMID: 4288894]

[EC created 1972]

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