IUBMB Enzyme Nomenclature


Accepted name: UTP—glucose-1-phosphate uridylyltransferase

Reaction: UTP + α-D-glucose 1-phosphate = diphosphate + UDP-glucose

For diagram of reaction click here.

Other name(s): UDP glucose pyrophosphorylase; glucose-1-phosphate uridylyltransferase; UDPG phosphorylase; UDPG pyrophosphorylase; uridine 5'-diphosphoglucose pyrophosphorylase; uridine diphosphoglucose pyrophosphorylase; uridine diphosphate-D-glucose pyrophosphorylase; uridine-diphosphate glucose pyrophosphorylase

Systematic name: UTP:α-D-glucose-1-phosphate uridylyltransferase

Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, PDB, CAS registry number: 9026-22-6


1. Kalckar, H.M. The role of phosphoglycosyl compounds in the biosynthesis of nucleosides and nucleotides. Biochim. Biophys. Acta 12 (1953) 250-264.

2. Kamogawa, A. and Kurahashi, K. Purification and properties of uridinediphosphate glucose pyrophosphorylase from Escherichia coli K12. J. Biochem. (Tokyo) 57 (1965) 758-765. [PMID: 4284510]

3. Lobelle-Rich, P.A. and Reeves, R.E. Separation and characterization of two UTP-utilizing hexose phosphate uridylyltransferases from Entamoeba histolytica. Mol. Biochem. Parasitol. 7 (1983) 173-182. [PMID: 6304512]

4. Smith, E.E.B. and Mills, G.T. The uridyl transferase of mammary gland. Biochim. Biophys. Acta 18 (1955) 152 only.

5. Turnquist, R.L., Gillett, T.A. and Hansen, R.G. Uridine diphosphate glucose pyrophosphorylase. Crystallization and properties of the enzyme from rabbit liver and species comparisons. J. Biol. Chem. 249 (1974) 7695-7700. [PMID: 4436332]

[EC created 1961]

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