IUBMB Enzyme Nomenclature


Accepted name: phosphatidylcholine synthase

Reaction: CDP-diacylglycerol + choline = CMP + phosphatidylcholine

Other name(s): CDP-diglyceride-choline O-phosphatidyltransferase

Systematic name: CDP-diacylglycerol:choline O-phosphatidyltransferase

Comments: Requires divalent cations, with Mn2+ being more effective than Mg2+.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 243666-86-6


1. de Rudder, K.E.E., Sohlenkamp, C. and Geiger, O. Plant-exudated choline is used for rhizobial membrane lipid biosynthesis by phosphatidylcholine synthase. J. Biol. Chem. 274 (1999) 20011-20016. [PMID: 10391951]

2. Sohlenkamp, C., de Rudder, K.E.E., Röhrs, V., López-Lara, I.M. and Geiger, O. Cloning and characterization of the gene for phosphatidylcholine synthase. J. Biol. Chem. 275 (2000) 18919-18925. [PMID: 10858449]

[EC created 2001]

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