IUBMB Enzyme Nomenclature

EC 2.7.8.5

Accepted name: CDP-diacylglycerol—glycerol-3-phosphate 3-phosphatidyltransferase

Reaction: CDP-diacylglycerol + sn-glycerol 3-phosphate = CMP + 3(3-sn-phosphatidyl)-sn-glycerol 1-phosphate

Other name(s): glycerophosphate phosphatidyltransferase; 3-phosphatidyl-1'-glycerol-3'-phosphate synthase; CDP-diacylglycerol:glycerol-3-phosphate phosphatidyltransferase; cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDP-diglyceride):sn-glycerol-3-phosphate phosphatidyltransferase; phosphatidylglycerophosphate synthase; phosphatidylglycerolphosphate synthase; PGP synthase; CDP-diacylglycerol-sn-glycerol-3-phosphate 3-phosphatidyltransferase; CDP-diacylglycerol:sn-glycero-3-phosphate phosphatidyltransferase; glycerol phosphate phosphatidyltransferase; glycerol 3-phosphate phosphatidyltransferase; phosphatidylglycerol phosphate synthase; phosphatidylglycerol phosphate synthetase; phosphatidylglycerophosphate synthetase; sn-glycerol-3-phosphate phosphatidyltransferase

Systematic name: CDP-diacylglycerol:sn-glycerol-3-phosphate 3-phosphatidyltransferase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9068-49-9

References:

1. Bleasdale, J.E. and Johnston, J.M. CMP-dependent incorporation of [14C]glycerol 3-phosphate into phosphatidylglycerol and phosphatidylglycerol phosphate by rabbit lung microsomes. Biochim. Biophys. Acta 710 (1982) 377-390. [PMID: 7074121]

2. Hirabayashi, T. Larson, T.J. and Dowhan, W. Membrane-associated phosphatidylglycerophosphate synthetase from Escherichia coli: Purification by substrate affinity chromatography on cytidine 5'-diphospho-1,2-diacyl-sn-glycerol sepharose. Biochemistry 15 (1976) 5205-5211. [PMID: 793612]

[EC 2.7.8.5 created 1972, modified 1976]


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