IUBMB Enzyme Nomenclature


Accepted name: pyruvate, phosphate dikinase

Reaction: ATP + pyruvate + phosphate = AMP + phosphoenolpyruvate + diphosphate

Other names: pyruvate, orthophosphate dikinase; pyruvate-phosphate dikinase (phosphorylating); pyruvate, phosphate dikinase; pyruvate-inorganic phosphate dikinase; pyruvate-phosphate dikinase; pyruvate-phosphate ligase; pyruvic-phosphate dikinase; pyruvic-phosphate ligase; pyruvate, Pi dikinase; PPDK

Systematic name: ATP:pyruvate, phosphate phosphotransferase

Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, PDB, CAS registry number: 9027-40-1


1. Hatch, M.D. and Slack, C.R. A new enzyme for the interconversion of pyruvate and phosphopyruvate and its role in the C4 dicarboxylic acid pathway of photosynthesis. Biochem. J. 106 (1968) 141-146. [PMID: 4305612]

2. Reeves, R.E. A new enzyme with the glycolytic function of pyruvate kinase. J. Biol. Chem. 243 (1968) 3202-3204. [PMID: 4297474]

3. Reeves, R.E. Pyruvate, phosphate dikinase from Bacteroides symbiosus. Biochem. J. 125 (1971) 531-539. [PMID: 5144757]

4. Reeves, R.E., Menzies, R.A. and Hsu, D.S. The pyruvate-phosphate dikinase reaction. The fate of phosphate and the equilibrium. J. Biol. Chem. 243 (1968) 5486-5491. [PMID: 4302788]

[EC created 1972]

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