IUBMB Enzyme Nomenclature


Accepted name: galactosylceramide sulfotransferase

Reaction: 3'-phosphoadenylyl sulfate + a galactosylceramide = adenosine 3',5'-bisphosphate + a galactosylceramidesulfate

Glossary: 3'-phosphoadenylyl sulfate = PAPS

Other names: GSase; 3'-phosphoadenosine-5'-phosphosulfate-cerebroside sulfotransferase; galactocerebroside sulfotransferase; galactolipid sulfotransferase; glycolipid sulfotransferase; glycosphingolipid sulfotransferase

Systematic name: 3'-phosphoadenylyl-sulfate:galactosylceramide 3'-sulfotransferase

Comments: Also acts on lactosylceramide.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9081-06-5


1. McKhann, G.M., Levy, R. and Ho, W. Metabolism of sulfatides. I. The effect of galactocerebrosides on the synthesis of sulfatides. Biochem. Biophys. Res. Commun. 20 (1965) 109-113. [PMID: 5850675]

2. Sakakibara, N., Gasa, S., Kamio, K., Makita, A. and Koyanagi, T. Association of elevated sulfatides and sulfotransferase activities with human renal cell carcinoma. Cancer Res. 49 (1989) 335-339. [PMID: 2562926]

[EC created 1972, modified 1976]

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