IUBMB Enzyme Nomenclature


Accepted name: steroid sulfotransferase

Reaction: 3'-phosphoadenylyl sulfate + a phenolic steroid = adenosine 3',5'-bisphosphate + steroid O-sulfate

Glossary: 3'-phosphoadenylyl sulfate = PAPS

Other names: steroid alcohol sulfotransferase

Systematic name: 3'-phosphoadenylyl-sulfate:phenolic-steroid sulfotransferase

Comments: Broad specificity resembling EC alcohol sulfotransferase, but also acts on estrone.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9032-76-2


1. Adams, J.B. and McDonald, D. Enzymic synthesis of steroid sulphates. XIII. Isolation and properties of dehydroepiandrosterone sulphotransferase from human foetal adrenals. Biochim. Biophys. Acta 615 (1980) 275-278. [PMID: 6932974]

[EC created 1984]

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