IUBMB Enzyme Nomenclature

EC 2.8.2.17

Accepted name: chondroitin 6-sulfotransferase

Reaction: 3'-phosphoadenylyl sulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate

For diagram click here.

Glossary: 3'-phosphoadenylyl sulfate = PAPS

Other names: chondroitin 6-O-sulfotransferase; 3'-phosphoadenosine 5'-phosphosulfate (PAPS):chondroitin sulfate sulfotransferase; terminal 6-sulfotransferase

Systematic name: 3'-phosphoadenylyl-sulfate:chondroitin 6'-sulfotransferase

Comments: The sulfation is at the 6-position of N-acetylgalactosamine residues of chondroitin. Not identical with EC 2.8.2.5 chondroitin 4-sulfotransferase.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 37292-93-6

References:

1. Habuchi, O. and Miyashita, N. Separation and characterization of chondroitin 6-sulfotransferase and chondroitin 4-sulfotransferase from chick embryo cartilage. Biochim. Biophys. Acta 717 (1982) 414-421. [PMID: 6957247]

[EC 2.8.2.17 created 1986]


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