IUBMB Enzyme Nomenclature


Accepted name: estrone sulfotransferase

Reaction: 3'-phosphoadenylyl sulfate + estrone = adenosine 3',5'-bisphosphate + estrone 3-sulfate

Glossary: 3'-phosphoadenylyl sulfate = PAPS

Other names: 3'-phosphoadenylyl sulfate-estrone 3-sulfotransferase; estrogen sulfotransferase; estrogen sulphotransferase; oestrogen sulphotransferase; 3'-phosphoadenylylsulfate:oestrone sulfotransferase

Systematic name: 3'-phosphoadenylyl-sulfate:estrone 3-sulfotransferase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9026-06-6


1. Adams, J.B. and Poulos, A. Enzymic synthesis of steroid sulphates. 3. Isolation and properties of estrogen sulphotransferase of bovine adrenal glands. Biochim. Biophys. Acta 146 (1967) 493-508. [PMID: 4965224]

2. Rozhin, J., Zemlicka, J. and Brooks, S.C. Studies on bovine adrenal estrogen sulfotransferase. Inhibition and possible involvement of adenine-estrogen stacking. J. Biol. Chem. 252 (1967) 7214-7220.

3. Adams, J.B., Ellyard, R.K. and Low, J. Enzymic synthesis of steroid sulphates. IX. Physical and chemical properties of purified oestrogen sulphotransferase from bovine adrenal glands. The nature of its isoenzymic forms and a proposed model to explain its wave-like kinetics. Biochem. Biophys. Acta 370 (1974) 160-188.

[EC created 1965]

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