Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (NC-IUBMB)

Enzyme Nomenclature. Recommendations

http://www.chem.qmul.ac.uk/iubmb/enzyme/EC3/

EC 3. Hydrolase Nomenclature

Contents

Introduction

1. List of Accepted names EC 3 linked to a separate file for each enzyme. EC 3.1 to EC 3.3 and EC 3.4 to EC 3.12

2. List of Accepted names EC 3 linked to files with up to 50 enzymes. EC 3.1 to EC 3.3 and EC 3.4 to EC 3.12

EC 3 Hydrolases

NumberNameEnzyme file type
EC 3.1 Acting on ester bondsseparateup to 50
EC 3.1.1Carboxylic ester hydrolasesseparateup to 50
EC 3.1.2Thioester hydrolasesseparateup to 50
EC 3.1.3Phosphoric monoester hydrolasesseparateup to 50
EC 3.1.4Phosphoric diester hydrolasesseparateup to 50
EC 3.1.5Triphosphoric monoester hydrolasesseparateup to 50
EC 3.1.6Sulfuric ester hydrolasesseparateup to 50
EC 3.1.7Diphosphoric monoester hydrolasesseparateup to 50
EC 3.1.8Phosphoric triester hydrolasesseparateup to 50
EC 3.1.11Exodeoxyribonucleases producing 5'-phosphomonoestersseparateup to 50
EC 3.1.12Exodeoxyribonucleases producing 3'-phosphomonoestersseparateup to 50
EC 3.1.13Exoribonucleases producing 5'-phosphomonoestersseparateup to 50
EC 3.1.14Exoribonucleases producing 3'-phosphomonoestersseparateup to 50
EC 3.1.15Exonucleases active with either ribo- or deoxyribonucleic acids
and producing 5'-phosphomonoesters
separateup to 50
EC 3.1.16Exonucleases active with either ribo- or deoxyribonucleic acids
and producing 3'-phosphomonoesters
separateup to 50
EC 3.1.21Endodeoxyribonucleases producing 5'-phosphomonoestersseparateup to 50
EC 3.1.22Endodeoxyribonucleases producing 3'-phosphomonoestersseparateup to 50
EC 3.1.25Site-specific endodeoxyribonucleases specific for altered basesseparateup to 50
EC 3.1.26Endoribonucleases producing 5'-phosphomonoestersseparateup to 50
EC 3.1.27Endoribonucleases producing 3'-phosphomonoestersseparateup to 50
EC 3.1.30Endoribonucleases active with either ribo- or deoxyribonucleic acids
and producing 5'-phosphomonoesters
separateup to 50
EC 3.1.31Endoribonucleases active with either ribo- or deoxyribonucleic acids
and producing 3'-phosphomonoesters
separateup to 50
EC 3.2 Glycosylasesseparateup to 50
EC 3.2.1Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compoundsseparateup to 50
EC 3.2.2Hydrolysing N-glycosyl compoundsseparateup to 50
EC 3.2.3Hydrolysing S-Glycosyl compounds (discontinued)separateup to 50
EC 3.3Acting on ether bondsseparateup to 50
EC 3.3.1Thioether and trialkylsulfonium hydrolasesseparateup to 50
EC 3.3.2Ether hydrolasesseparateup to 50
EC 3.4Acting on peptide bonds (Peptidases)separateup to 50
EC 3.4.11Aminopeptidasesseparateup to 50
EC 3.4.13Dipeptidasesseparateup to 50
EC 3.4.14Dipeptidyl-peptidases and tripeptidyl-peptidasesseparateup to 50
EC 3.4.15Peptidyl-dipeptidasesseparateup to 50
EC 3.4.16Serine-type carboxypeptidasesseparateup to 50
EC 3.4.17Metallocarboxypeptidasesseparateup to 50
EC 3.4.18Cysteine-type carboxypeptidasesseparateup to 50
EC 3.4.19Omega peptidasesseparateup to 50
EC 3.4.21Serine endopeptidasesseparateup to 50
EC 3.4.22Cysteine endopeptidasesseparateup to 50
EC 3.4.23Aspartic endopeptidasesseparateup to 50
EC 3.4.24Metalloendopeptidasesseparateup to 50
EC 3.4.25Threonine endopeptidasesseparateup to 50
EC 3.4.99Endopeptidases of unknown catalytic mechanismseparateup to 50
EC 3.5Acting on carbon-nitrogen bonds, other than peptide bondsseparateup to 50
EC 3.5.1In linear amidesseparateup to 50
EC 3.5.2In cyclic amidesseparateup to 50
EC 3.5.3In linear amidinesseparateup to 50
EC 3.5.4In cyclic amidinesseparateup to 50
EC 3.5.5In nitrilesseparateup to 50
EC 3.5.99In other compoundsseparateup to 50
EC 3.6Acting on acid anhydridesseparateup to 50
EC 3.6.1In phosphorus-containing anhydridesseparateup to 50
EC 3.6.2In sulfonyl-containing anhydridesseparateup to 50
EC 3.6.3Acting on acid anhydrides; catalysing transmembrane movement of substancesseparateup to 50
EC 3.6.4Acting on acid anhydrides; involved in cellular and subcellular movementseparateup to 50
EC 3.6.5Acting on GTP; involved in cellular and subcellular movementseparateup to 50
EC 3.7Acting on carbon-carbon bondsseparateup to 50
EC 3.7.1In ketonic substancesseparateup to 50
EC 3.8Acting on halide bondsseparateup to 50
EC 3.8.1In C-halide compoundsseparateup to 50
EC 3.9Acting on phosphorus-nitrogen bondsseparateup to 50
EC 3.10Acting on sulfur-nitrogen bondsseparateup to 50
EC 3.11Acting on carbon-phosphorus bondsseparateup to 50
EC 3.12Acting on sulfur-sulfur bondsseparateup to 50
EC 3.13Acting on carbon-sulfur Bondsseparateup to 50


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