IUBMB Enzyme Nomenclature


Accepted name: poly(A)-specific ribonuclease

Reaction: Exonucleolytic cleavage of poly(A) to 5'-AMP

Other name(s): 3'-exoribonuclease; 2',3'-exoribonuclease

Comments: Cleaves poly(A) in either the single- or double-stranded form.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 110541-21-4


1. Schröder, H.C., Zahn, R.K., Dose, K. and Müller, E.G. Purification and characterization of a poly(A)-specific exoribonuclease from calf thymus. J. Biol. Chem. 255 (1980) 4535-4538. [PMID: 6246077]

[EC created 1984]

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