IUBMB Enzyme Nomenclature


Accepted name: acyl-CoA hydrolase

Reaction: acyl-CoA + H2O = CoA + a carboxylate

Other name(s): acyl coenzyme A thioesterase; acyl-CoA thioesterase; acyl coenzyme A hydrolase; thioesterase B; thioesterase II; acyl-CoA thioesterase

Systematic name: acyl-CoA hydrolase

Comments: Broad specificity for medium- to long-chain acyl-CoA. Insensitive to NAD+ (cf. EC ADP-dependent medium-chain-acyl-CoA hydrolase)

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 37270-64-7


1. Alexson, S.E.H., Svensson, L.T. and Nedergaard, J. NADH-sensitive propionyl-CoA hydrolase in brown-adipose-tissue mitochondria in the rat.Biochim. Biophys. Acta 1005 (1989) 13-19. [PMID: 2570608]

[EC created 1992]

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