IUBMB Enzyme Nomenclature


Accepted name: deoxyribonuclease (pyrimidine dimer)

Reaction: Endonucleolytic cleavage near pyrimidine dimers to products with 5'-phosphate

Other name(s): endodeoxyribonuclease (pyrimidine dimer); endodeoxyribonuclease (pyrimidine dimer); bacteriophage T4 endodeoxyribonuclease V; T4 endonuclease V

Comments: Acts on a damaged strand, 5' from the damaged site.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 66143-22-4


1. Braun, A.G., Radman, M. and Grossman, L. Enzymic repair of DNA: sites of hydrolysis by the Escherichia coli endonuclease specific for pyrimidine dimers (corendonuclease II) Biochemistry 15 (1976) 4116-4120.

2. Riazuddin, S. and Grossman, L. Micrococcus luteus correndonucleases. II. Mechanism of action of two endonucleases specific for DNA containing pyrimidine dimers. J. Biol. Chem. 252 (1977) 6287-6293. [PMID: 330526]

[EC created 1978]

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