IUBMB Enzyme Nomenclature


Accepted name: ribonuclease alpha

Reaction: Endonucleolytic cleavage to 5'-phosphomonoester

Other name(s): 2'-O-methyl RNase

Comments: Specific for O-methylated RNA.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Norton, J. and Roth, J.S. A ribonuclease specific for 2'-O-methylated ribonucleic acid. J. Biol. Chem. 242 (1967) 2029-2034. [PMID: 6022850]

[EC created 1978]

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