IUBMB Enzyme Nomenclature


Accepted name: ribonuclease T1

Reaction: Two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Gp with 2',3'-cyclic phosphate intermediates

Other name(s): guanyloribonuclease; Aspergillus oryzae ribonuclease; RNase N1; RNase N2; ribonuclease N3; ribonuclease U1; ribonuclease F1; ribonuclease Ch; ribonuclease PP1; ribonuclease SA; RNase F1; ribonuclease C2; binase; RNase Sa; guanyl-specific RNase; RNase G; RNase T1; ribonuclease guaninenucleotido-2'-transferase (cyclizing); ribonuclease N3; ribonuclease N1

Comments: Formerly EC and EC

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9026-12-4


1. Kasai, K., Uchida, T., Egami, F., Yoshida, K. and Nomoto, M. Purification and crystallization of ribonuclease N1 from Neurospora crassa. J. Biochem. (Tokyo) 66 (1969) 389-396. [PMID: 5348588]

2. Takahashi, K. The structure and function of ribonuclease T1. I. Chromatographic purification and properties of ribonuclease T1. J. Biochem. (Tokyo) 49 (1961) 1-8.

[EC created 1961 as EC, transferred 1965 to EC, reinstated 1972 as EC, transferred 1978 to EC]

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