IUBMB Enzyme Nomenclature

EC 3.1.27.6

Accepted name: Enterobacter ribonuclease

Reaction: Endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates

Comments: Preference for cleavage at CpA. Homopolymers of A, U or G are not hydrolysed.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 395640-99-0

References:

1. Levy, C.C. and Goldman, P. Residue specificity of a ribonuclease which hydrolyzes polycytidylic acid. J. Biol. Chem. 245 (1970) 3257-3262. [Medline UI: 70250418]

2. Marotta, C.A., Levy, C.C., Weissman, S.M. and Varricchio, F. Preferred sites of digestion of a ribonuclease from Enterobacter sp. in the sequence analysis of Bacillus stearothermophilus 5S ribonucleic acid. Biochemistry 12 (1973) 2901-2904. [Medline UI: 73221045]

[EC 3.1.27.6 created 1978, modified 1981]


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