IUBMB Enzyme Nomenclature


Accepted name: 4-phytase

Reaction: myo-inositol hexakisphosphate + H2O = 1D-myo-inositol 1,2,3,5,6-pentakisphosphate + phosphate

Other name(s): 6-phytase (name based on 1L-numbering system and not 1D-numbering); phytase; phytate 6-phosphatase; myo-inositol-hexakisphosphate 6-phosphohydrolase (name based on 1L-numbering system and not 1D-numbering)

Systematic name: myo-inositol-hexakisphosphate 4-phosphohydrolase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9001-89-2


1. Johnson, L.F. and Tate, M.E. The structure of myo-inositol pentaphosphates. Ann. N.Y. Acad. Sci. 165 (1969) 526-532. [PMID: 4310376]

2. Tomlinson, R.V. and Ballou, C.E. Myoinositol polyphosphate intermediates in the dephosphorylation of phytic acid by phytase. Biochemistry 1 (1962) 166-171.

3. Lim, P.E. and Tate, M.E. The phytases. II. Properties of phytase fractions F1 and F2 from wheat bran and the myo-inositol phosphates produced by fraction F2. Biochim. Biophys. Acta 302 (1973) 316-328. [PMID: 4349266]

4. Cosgrove, D.J. Inositol phosphates: their chemistry, biochemistry, and physiology., Elsevier, Amsterdam, 1980

[EC created 1972, modified 1976, modified 2002]

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