Reaction: A nucleotide + H2O = a nucleoside + phosphate
Other name(s): nucleotide phosphatase; nucleotide-specific phosphatase; NSP I; NSP II; deoxyribonucleoside-activated nucleotidase (DAN); deoxyinosine-activated nucleotidase (DIAN); acid nucleotidase
Systematic name: nucleotide phosphohydrolase
Comments: A wide specificity for 2', 3'- and 5'- nucleotides; also hydrolyses glycerol phosphate and 4-nitrophenyl phosphate.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9033-33-4
1. Arsenis, C. and Touster, O. Purification and properties of an acid nucleotidase from rat liver lysosomes. J. Biol. Chem. 243 (1968) 5702-5708. [PMID: 5699060]