Reaction: A 5'-phosphopolynucleotide + H2O = a polynucleotide + phosphate
Other name(s): 5'-polynucleotidase
Systematic name: polynucleotide 5'-phosphohydrolase
Comments: Does not act on nucleoside monophosphates. Induced in Escherichia coli by T-even phages.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 37288-17-8
1. Becker, A. and Hurwitz, J. The enzymatic cleavage of phosphate termini from polynucleotides. J. Biol. Chem. 242 (1967) 936-950. [PMID: 4289819]