IUBMB Enzyme Nomenclature


Accepted name: guanosine-3',5'-bis(diphosphate) 3'-diphosphatase

Reaction: guanosine 3',5'-bis(diphosphate) + H2O = GDP + diphosphate

Glossary: GDP = guanosine 5'-diphosphate

Other name(s): guanosine-3',5'-bis(diphosphate) 3'-pyrophosphatase; PpGpp-3'-pyrophosphohydrolase; PpGpp phosphohydrolase

Systematic name: guanosine-3',5'-bis(diphosphate) 3'-diphosphohydrolase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 70457-12-4


1. Heinemeyer, E.-A. and Richter, D. Characterization of the guanosine 5'-triphosphate 3'-diphosphate and guanosine 5'-diphosphate 3'-diphosphate degradation reaction catalyzed by a specific pyrophosphorylase from Escherichia coli. Biochemistry 17 (1978) 5368-5372. [PMID: 365225]

2. Richter, D., Fehr, S. and Harder, R. The guanosine 3',5'-bis(diphosphate) (ppGpp) cycle. Comparison of synthesis and degradation of guanosine 3',5'-bis(diphosphate) in various bacterial systems. Eur. J. Biochem. 99 (1979) 57-64. [PMID: 114395]

[EC created 1980]

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