IUBMB Enzyme Nomenclature


Accepted name: maltose-6'-phosphate glucosidase

Reaction: α-maltose 6′-phosphate + H2O = D-glucose + D-glucose 6-phosphate

Other name(s): phospho-α-glucosidase; maltose-6'-phosphate 6-phosphoglucohydrolase

Systematic name: α-maltose-6'-phosphate 6-phosphoglucohydrolase

Comments: Hydrolyses a variety of 6-phospho-α-D-glucosides, including α-maltose 6'-phosphate, α,α-trehalose 6-phosphate, sucrose 6-phosphate and p-nitrophenyl-α-D-glucopyranoside 6-phosphate (as a chromogenic substrate). The enzyme is activated by FeII, MnII, CoII and NiII. It is rapidly inactivated in air.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 98445-08-0


1. Thompson, J., Gentry-Weeks, C.R., Nguyen, N.Y., Folk, J.E., Robrish, S.A. Purification from Fusobacterium mortiferum ATCC 25557 of a 6-phosphoryl-O-α-D-glucopyranosyl:6-phosphoglucohydrolase that hydrolyses maltose 6-phosphate and related phospho-α-D-glucosides. J. Bacteriol. 177 (1995) 2505-2512. [PMID: 7730284]

[EC created 1989, modified 1999]

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