IUBMB Enzyme Nomenclature


Accepted name: glycyrrhizinate β-glucuronidase

Reaction: glycyrrhizinate + H2O = (1→2)-β-D-glucuronosyl-D-glucuronate + glycyrrhetinate

Other name(s): glycyrrhizin β-hydrolase; glycyrrhizin hydrolase; glycyrrhizinic acid hydrolase

Systematic name: glycyrrhizinate glucuronosylhydrolase

Comments: The enzyme from Aspergillus niger is specific for the hydrolysis of the triterpenoid glycoside glycyrrhizinate from roots of Glycyrrhiza sp.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 102484-56-0


1. Muro, T., Kuramoto, T., Imoto, K. and Okada, S. Purification and some properties of glycyrrhizinic acid hydrolase from Aspergillus niger GRM3. Agric. Biol. Chem. 50 (1986) 687-692.

[EC created 1989]

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