Reaction: 2-O-(6-phospho-α-D-mannosyl)-D-glycerate + H2O = D-mannose 6-phosphate + D-glycerate
Other name(s): 2-O-(6-phospho-mannosyl)-D-glycerate hydrolase; α-mannosidase (ambiguous); mngB (gene name)
Systematic name: 2-O-(6-phospho-α-D-mannosyl)-D-glycerate acylhydrolase
Comments: The enzyme participates in the mannosylglycerate degradation pathway of some bacteria. Mannosylglycerate is phosphorylated during transport into the cell, and the phosphorylated form is hydrolysed by this enzyme.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:
1. Sampaio, M.M., Chevance, F., Dippel, R., Eppler, T., Schlegel, A., Boos, W., Lu, Y.J. and Rock, C.O. Phosphotransferase-mediated transport of the osmolyte 2-O-α-mannosyl-D-glycerate in Escherichia coli occurs by the product of the mngA (hrsA) gene and is regulated by the mngR (farR) gene product acting as repressor. J. Biol. Chem. 279 (2004) 5537-5548. [PMID: 14645248]