IUBMB Enzyme Nomenclature


Accepted name: galactosylceramidase

Reaction: a D-galactosyl-N-acylsphingosine + H2O = D-galactose + an N-acylsphingosine

Other name(s): cerebroside galactosidase; galactocerebroside.β-galactosidase; galactosylcerebrosidase; galactocerebrosidase; ceramide galactosidase; galactocerebroside galactosidase; galactosylceramide.β-galactosidase; cerebroside β-galactosidase; galactosylceramidase I; β-galactosylceramidase; galactocerebroside-β-D-galactosidase; lactosylceramidase I; β-galactocerebrosidase; lactosylceramidase

Systematic name: D-galactosyl-N-acylsphingosine galactohydrolase

Comments: cf. EC glycosylceramidase.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9027-89-8


1. Brady, R.O., Gal, A.E., Kanfer, J.N. and Bradley, R.M. The metabolism of glucocerebrosides. 3. Purification and properties of a glucosyl- and galactosylceramide-cleaving enzyme from rat intestinal tissue. J. Biol. Chem. 240 (1965) 3766-3770. [PMID: 5320641]

[EC created 1972]

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