Reaction: Hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-α-D-galactosaminides
Other name(s): α-acetylgalactosaminidase; N-acetyl-α-D-galactosaminidase; N-acetyl-α-galactosaminidase
Systematic name: α-N-acetyl-D-galactosaminide N-acetylgalactosaminohydrolase
Comments: Splits N-acetylgalactosaminyl groups from O-3 of Ser and Thr.
Links to other databases: BRENDA, EXPASY, KEGG, CAS registry number: 9075-63-2
References:
1. Tuppy, H. and Staudenbauer, W.L. The action on soluble blood group A substances of an α-N-acetylgalactosaminidase from Helix pomatia. Biochemistry 5 (1966) 1742-1747. [PMID: 6006833]
2. Weissmann, B. and Hinrichsen, D.F. Mammalian α-acetylgalactosaminidase. Occurrence, partial purification, and action on linkages in submaxillary mucins. Biochemistry 8 (1969) 2034-2043. [PMID: 5785223]
3. Werries, E., Wollek, E., Gottschalk, A. and Buddecke, E. Separation of N-acetyl-α-glucosaminidase and N-acetyl-α-galactosaminidase from ox spleen. Cleavage of the O-glycosidic linkage between carbohydrate and polypeptide in ovine and bovine submaxillary glycoprotein by N-acetyl-α-galactosaminidase. Eur. J. Biochem. 10 (1969) 445-449. [PMID: 5348072]