Reaction: S-methyl-5'-thioadenosine + H2O = S-methyl-5-thio-D-ribose + adenine
For diagram click here.
Other name(s): 5'-methylthioadenosine nucleosidase; MTA nucleosidase; MeSAdo nucleosidase; methylthioadenosine methylthioribohydrolase
Systematic name: S-methyl-5'-thioadenosine adeninehyrolase
Comments: Does not act on S-adenosylhomocysteine. cf. EC 220.127.116.11 adenosylhomocysteine nucleosidase.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 50812-28-7
1. Guranowski, A.B., Chiang, P.K. and Cantoni, G.L. 5'-Methylthioadenosine nucleosidase. Purification and characterization of the enzyme from Lupinus luteus seeds. Eur. J. Biochem. 114 (1981) 293-299. [PMID: 6783408]