IUBMB Enzyme Nomenclature


Accepted name: futalosine hydrolase

Reaction: futalosine + H2O = dehypoxanthine futalosine + hypoxanthine

For diagram of reaction click here.

Glossary: futalosine = 3-(3-((3S,4R)-3,4-dihydroxy-5-(6-oxo-3H-purin-9(6H)-yl)tetrahydrofuran-2-yl)propanoyl)benzoate
dehypoxanthine futalosine = 7-(3-carboxyphenyl)-D-ribo-7-dehydro-5,6-dideoxyheptose

Other name(s): futalosine nucleosidase; MqnB

Systematic name: futalosine ribohydrolase

Comments: This enzyme, which is specific for futalosine, catalyses the second step of a novel menaquinone biosynthetic pathway that is found in some prokaryotes.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Hiratsuka, T., Furihata, K., Ishikawa, J., Yamashita, H., Itoh, N., Seto, H. and Dairi, T. An alternative menaquinone biosynthetic pathway operating in microorganisms. Science 321 (2008) 1670-1673. [PMID: 18801996]

[EC created 2008]

Return to EC 3.2.2 home page
Return to EC 3.2 home page
Return to EC 3 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page