IUBMB Enzyme Nomenclature

EC 3.4.11.23

Accepted name: PepB aminopeptidase

Reaction: Release of an N-terminal amino acid, Xaa, from a peptide or arylamide. Xaa is preferably Glu or Asp but may be other amino acids, including Leu, Met, His, Cys and Gln

Other name(s): Salmonella enterica serovar Typhimurium peptidase B

Comments: A 270-kDa protein composed of six 46.3-kDa subunits. The pH optimum is in the alkaline range and activity is stimulated by KCl. In peptidase family M17.

Links to other databases: BRENDA, EXPASY, KEGG, MEROPS, Metacyc, CAS registry number: 928346-44-5

References:

1. Mathew, Z., Knox, T.M. and Miller, C.G. Salmonella enterica serovar Typhimurium peptidase B is a leucyl aminopeptidase with specificity for acidic amino acids. J. Bacteriol. 182 (2000) 3383-3393. [PMID: 10852868]

[EC 3.4.11.23 created 2003]


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