IUBMB Enzyme Nomenclature


Accepted name: dipeptidyl-dipeptidase

Reaction: Preferential release of dipeptides from a tetrapeptide, e.g. Ala-GlyAla-Gly. Acts more slowly on Ala-AlaAla-Ala and Gly-GlyGly-Gly

Other names: dipeptidyl tetrapeptide hydrolase; dipeptidyl ligase; tetrapeptide dipeptidase

Comments: A thiol-activated peptidase from cabbage (Brassica oleracea). Tetrapeptides are formed from Ala-Ala, Gly-Gly, Ala-Gly and Gly-Ala

Links to other databases: BRENDA, EXPASY, KEGG, MEROPS, Metacyc, CAS registry number: 91608-92-3


1. Eng, F.W.H.T. Dipeptidyl tetrapeptide hydrolase, a new enzyme with dipeptidyl ligase activity. Can. J. Biochem. Cell. Biol. 62 (1984) 516-528

[EC created 1989]

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