IUBMB Enzyme Nomenclature


Accepted name: cathepsin G

Reaction: Specificity similar to chymotrypsin C

Other name(s): chymotrypsin-like proteinase; neutral proteinase

Comments: From azurophil granules of polymorphonuclear leukocytes. In peptidase family S1 (trypsin family)

Links to other databases: BRENDA, EXPASY, KEGG, MEROPS, Metacyc, PDB, CAS registry number: 56645-49-9


1. Barrett, A.J. Cathepsin G. Methods Enzymol. 80 (1981) 561-565. [PMID: 7341917]

2. Tanaka, T., Minematsu, Y., Reilly, C.F., Travis, J. and Powers, J.C. Human leukocyte cathepsin G. Subsite mapping with 4-nitroanilides, chemical modification, and effect of possible cofactors. Biochemistry 24 (1985) 2040-2047. [PMID: 4016099]

3. Hohn, P.A., Popescu, N.C., Hanson, R.D., Salvesen, G. and Ley, T.J. Genomic organization and chromosomal localization of the human cathepsin G gene. J. Biol. Chem. 264 (1989) 13412-13419. [PMID: 2569462]

[EC created 1978]

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