IUBMB Enzyme Nomenclature

EC 3.4.21.81

Accepted name: streptogrisin B

Reaction: Hydrolysis of proteins with trypsin-like specificity

Other names: Streptomyces griseus protease B; pronase B; serine proteinase B; Streptomyces griseus proteinase B; Streptomyces griseus proteinase 1; Streptomyces griseus serine proteinase B

Comments: From Streptomyces griseus. A component of Pronase, in peptidase family S1 (trypsin family), distinct from Streptomyces trypsin

Links to other databases: BRENDA, EXPASY, KEGG, MEROPS, Metacyc, PDB, CAS registry number: 55071-87-9

References

1. Jurasek, L., Fackre, D. and Smillie, L.B. Remarkable homology about the disulfide bridges of a trypsin-like enzyme from Streptomyces griseus. Biochem. Biophys. Res. Commun. 37 (1969) 99-105. [PMID: 4899581]

2. Fujinaga, M., Read, R.J., Sielecki, A., Ardelt, W., Laskowski, M., Jr and James, M.N.G. Refined crystal structure of the molecular complex of Streptomyces griseus protease B, a serine protease, with the third domain of the ovomucoid inhibitor from turkey. Proc. Natl. Acad. Sci. USA 79 (1982) 4868-4872. [PMID: 6750612]

3. Read, R.J., Fujinaga, M., Sielecki, A.R. and James, M.N.G. Structure of the complex of Streptomyces griseus protease B and the third domain of turkey ovomucoid inhibitor at 1.8-Å resolution. Biochemistry 22 (1983) 4420-4433. [PMID: 6414511]

4. Henderson, G., Krygsman, P., Liu, C.J., Davey, C.C. and Malek, L.T. Characterization and structure of genes for proteases A and B from Streptomyces griseus. J. Bacteriol. 169 (1987) 3778-3784 [PMID: 3112129]

5. Greenblatt, H.M., Ryan, C.A. and James, M.N.G. Structure of the complex of Streptomyces griseus proteinase B and polypeptide chymotrypsin inhibitor-1 from Russet Burbank potato tubers at 2.1 Å resolution. J. Mol. Biol. 205 (1989) 201-228. [PMID: 2494344]

[EC 3.4.21.81 created 1993]


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