IUBMB Enzyme Nomenclature


Accepted name: oligopeptidase B

Reaction: Hydrolysis of -Arg, -Lys bonds in oligopeptides, even when P1' residue is proline

Other names: protease II; Escherichia coli alkaline proteinase II; protease II

Comments: Known from Escherichia coli. Inhibited by Tos-Lys-CH2Cl. In peptidase family S9 (prolyl oligopeptidase family)

Links to other databases: BRENDA, EXPASY, KEGG, MEROPS, Metacyc, PDB, CAS registry number: 57657-67-7


1. Kanatani, A., Masuda, T., Shimoda, T., Misoka, F., Lin, X.S., Yoshimoto, T. and Tsuru, D. Protease II from Escherichia coli: sequencing and expression of the enzyme gene and characterization of the expressed enzyme. J. Biochem. (Tokyo) 110 (1991) 315-320. [PMID: 1769955]

[EC created 1993]

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