IUBMB Enzyme Nomenclature

EC 3.4.22.3

Accepted name: ficain

Reaction: Similar to that of papain

Other names: ficin; debricin; higueroxyl delabarre

Comments: The major proteolytic component of the latex of fig, Ficus glabrata. Cysteine endopeptidases with similar properties are present in other members of the large genus Ficus. In peptidase family C1 (papain family). Formerly EC 3.4.4.12

Links to other databases: BRENDA, EXPASY, KEGG, MEROPS, Metacyc, CAS registry number: 9001-33-6

References:

1. Liener, I.E. and Friedenson, B. Ficin. Methods Enzymol. 19 (1970) 261-273

2. Brocklehurst, K., Willenbrock, F. and Salih, E. Cysteine proteinases. In New Comprehensive Biochemistry Vol. 16, Hydrolytic Enzymes (Neuberger, A. and Brocklehurst, K. eds), pp. 39-158 (1987) Elsevier, Amsterdam

[EC 3.4.22.3 created 1961 as EC 3.4.4.12, transferred 1972 to EC 3.4.22.3]


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