IUBMB Enzyme Nomenclature


Accepted name: chymopapain

Reaction: Similar to that of papain

Other name(s): chymopapain A; chymopapain B; chymopapain S

Comments: The major endopeptidase of papaya (Carica papaya) latex. It has multiple chromatographic forms. In peptidase family C1 (papain family). Formerly EC

Links to other databases: BRENDA, EXPASY, KEGG, MEROPS, Metacyc, PDB, CAS registry number: 9001-09-6


1. Brocklehurst, K., Willenbrock, F. and Salih, E. Cysteine proteinases. In New Comprehensive Biochemistry Vol. 16, Hydrolytic Enzymes (Neuberger, A. and Brocklehurst, K., eds), pp. 39-158 (1987) Elsevier, Amsterdam

2. Jacquet, A., Kleinschmidt, T., Schnek, A.G., Looze, Y. and Braunitzer, G. The thiol proteinases from the latex of Carica papaya L. III. The primary structure of chymopapain. Biol. Chem. Hoppe-Seyler 370 (1989) 425-434. [PMID: 2500950]

3. Buttle, D.J., Dando, P.M., Coe, P.F., Sharp, S.L., Shepherd, S.T. and Barrett, A.J. The preparation of fully active chymopapain free of contaminating proteinases. Biol. Chem. Hoppe-Seyler 371 (1990) 1083-1088. [PMID: 2085414]

[EC created 1961 as EC, transferred 1972 to EC]

Return to EC 3.4.22 home page
Return to EC 3.4 home page
Return to EC 3 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page