IUBMB Enzyme Nomenclature


Accepted name: flavastacin

Reaction: Hydrolyses polypeptides on the amino-side of Asp in -XaaAsp-. Acts very slowly on -XaaGlu

Comments: A zinc metalloendopeptidase in peptidase family M12 (astacin family), secreted by the bacterium Flavobacterium meningosepticum . The specificity is similar to that of (EC, peptidyl-Asp metalloendopeptidase from Pseudomonas fragi but the two are reported to be structurally dissimilar

Links to other databases: BRENDA, EXPASY, KEGG, MEROPS, Metacyc, CAS registry number: 167973-66-2


1. Tarentino, A.L., Quinones, G., Grimwood, B.G., Hauer, C.R. and Plummer, T.H., Jr. Molecular cloning and sequence analysis of flavastacin: an O-glycosylated prokaryotic zinc metalloendopeptidase.Arch. Biochem. Biophys. 319 (1995) 281-285. [PMID: 7771796]

[EC created 2000]

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