Reaction: An N-acyl-L-amino acid + H2O = a carboxylate + an L-amino acid
Other name(s): dehydropeptidase II; histozyme; hippuricase; benzamidase; acylase I; hippurase; amido acid deacylase; L-aminoacylase; acylase; aminoacylase I; L-amino-acid acylase; α-N-acylaminoacid hydrolase; long acyl amidoacylase; short acyl amidoacylase
Systematic name: N-acyl-L-amino-acid amidohydrolase
Comments: Wide specificity; also hydrolyses dehydropeptides. Used in separating D- and L- amino acids
Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, PDB, CAS registry number: 9012-37-7
1. Birnbaum, S.M., Levintow, L., Kingsley, R.B. and Greenstein, J.P. Specificity of amino acid acylases. J. Biol. Chem. 194 (1952) 455-470.
2. Fones, W.S. and Lee, M. Hydrolysis of N-acyl derivatives of alanine and phenylalanine by acylase I and carboxypeptidase. J. Biol. Chem. 201 (1953) 847-856.
3. Park, R.W. and Fox, S.W. An acylase system related to the utilization of benzoylamino acids by Lactobacillus arabinosus. J. Biol. Chem. 235 (1960) 3193-3197.