Reaction: L-glutamine + H2O = L-glutamate + NH3
Systematic name: L-glutamine(L-asparagine) amidohydrolase
Comments: L-Asparagine is hydrolysed at 0.8 of the rate of L-glutamine; the D-isomers are also hydrolysed, but more slowly.
Links to other databases: BRENDA, EXPASY, KEGG, PDB, CAS registry number: 39335-03-0
References:
1. Roberts, J., Holcenberg, J.S. and Dolowy, W.C. Isolation, crystallization, and properties of Achromobacteraceae glutaminase-asparaginase with antitumor activity. J. Biol. Chem. 247 (1972) 84-90. [PMID: 5017769]