IUBMB Enzyme Nomenclature

EC 3.5.1.6

Accepted name: β-ureidopropionase

Reaction: N-carbamoyl-β-alanine + H2O = β-alanine + CO2 + NH3

Systematic name: N-carbamoyl-β-alanine amidohydrolase

Comments: The animal enzyme also acts on β-ureidoisobutyrate.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9027-27-4

References:

1. Campbell, L.L. Reductive degradation of pyrimidines. 5. Enzymatic conversion of N-carbamyl-β-alanine to β-alanine, carbon dioxide, and ammonia. J. Biol. Chem. 235 (1960) 2375-2378.

2. Caravaca, J. and Grisolia, S. Enzymatic decarbamylation of carbamyl β-alanine and carbamyl β-aminoisobutyric acid. J. Biol. Chem. 231 (1958) 357-365.

3. Traut, T.W. and Loechel, S. Pyrimidine catabolism: individual characterization of the three sequential enzymes with a new assay. Biochemistry 23 (1984) 2533-2539. [PMID: 6433973]

[EC 3.5.1.6 created 1961]


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