Reaction: Nω,Nω'-dimethyl-L-arginine + H2O = dimethylamine + L-citrulline
Other name(s): dimethylarginine dimethylaminohydrolase; NG,NG-dimethylarginine dimethylaminohydrolase; NG,NG-dimethyl-L-arginine dimethylamidohydrolase; ω,ωÕ-di-N-methyl-L-arginine dimethylamidohydrolase
Systematic name: Nω,Nω'-dimethyl-L-arginine dimethylamidohydrolase
Comments: Also acts on Nω-methyl-L-arginine.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 123644-75-7
1. Ogawa, T., Kimoto, M. and Sasaoka, K. Purification and properties of a new enzyme, NG, NG-dimethylarginine dimethylaminohydrolase, from rat kidney. J. Biol. Chem. 264 (1989) 10205-10209. [PMID: 2722865]