IUBMB Enzyme Nomenclature

EC 3.5.3.18

Accepted name: dimethylargininase

Reaction: Nω,Nω'-dimethyl-L-arginine + H2O = dimethylamine + L-citrulline

Other name(s): dimethylarginine dimethylaminohydrolase; NG,NG-dimethylarginine dimethylaminohydrolase; NG,NG-dimethyl-L-arginine dimethylamidohydrolase; ω,ω-di-N-methyl-L-arginine dimethylamidohydrolase

Systematic name: Nω,Nω'-dimethyl-L-arginine dimethylamidohydrolase

Comments: Also acts on Nω-methyl-L-arginine.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 123644-75-7

References:

1. Ogawa, T., Kimoto, M. and Sasaoka, K. Purification and properties of a new enzyme, NG, NG-dimethylarginine dimethylaminohydrolase, from rat kidney. J. Biol. Chem. 264 (1989) 10205-10209. [PMID: 2722865]

[EC 3.5.3.18 created 1992]


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