IUBMB Enzyme Nomenclature


Accepted name: guanine deaminase

Reaction: guanine + H2O = xanthine + NH3

Other name(s): guanase; guanine aminase; GAH

Systematic name: guanine aminohydrolase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9033-16-3


1. Hitchings, G.H. and Falco, E.A. The identification of guanine in extracts of Girella nigricans. The specificity of guanase. Proc. Natl. Acad. Sci. USA 30 (1944) 294-297.

2. Kalckar, H.M. Differential spectrophotometry of purine compounds by means of specific enzymes. III. Studies of the enzymes of purine metabolism. J. Biol. Chem. 167 (1947) 461-475.

3. Rabinowitz, J.C. and Barker, H.A. Purine fermentation by Clostridium cylindrosporum. II. Purine transformations. J. Biol. Chem. 218 (1956) 161-173.

[EC created 1961]

Return to EC 3.5.4 home page
Return to EC 3.5 home page
Return to EC 3 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page