Reaction: 2-aminomuconate + H2O = 4-oxalocrotonate + NH3
Systematic name: 2-aminomuconate aminohydrolase
Comments: Intermediate in the biodegradation of nitrobenzene by Pseudomonas pseudocaligenes JS45. The reaction is spontaneous in acid conditions.
Links to other databases: BRENDA, EXPASY, KEGG, CAS registry number:
References:
1. He, Z. and Spain, J.C. A novel 2-aminomuconate deaminase in the nitrobenzene degradation pathway of Pseudomonas pseudoalcaligenes JS45. J. Bacteriol. 180 (1998) 2502-2506. [PMID: 9573204]
2. He, Z, and Spain, J.C. Studies of the catabolic pathway of degradation of nitrobenzene by Pseudomonas pseudoalcaligenes JS45: removal of the amino group from 2-aminomuconic semialdehyde. Appl. Environ. Microbiol. 63 (1997) 4839-4843. [PMID: 9471964]